1. |
Zacchi, L.F., Dittmar, J.C., Mihalevic, M.J., Shewan, A.M., Schulz, B.L., Brodsky, J.F., Bernstein, K.A. (2017) A novel high-throughput yeast genetic screen for factors modifying protein levels of the Early-Onset Torsion Dystonia-associate variant torsinA∆E, Disease Models and Mechanisms, In press. |
2. |
Kondrashova O., Nguyen M., Shield-Artin K., Tinker A.V., Teng N.N.H., Harrell M.I., Kuiper M.J., Ho G.Y., Barker H., Jasin M., Prakash R., Kass E.M., Sullivan M.R., Brunette G.J., Bernstein K.A., Coleman R.L., Floquet A., Friedlander M., Kichenadasse G., O'Malley D.M., Oza A.M., Sun J.X., Robillard L., Maloney L., Bowtell D.D.L., Giordano H, Wakefield M.J., Kaufmann S.H., Simmons A.D., Harding T.C., Raponi M., McNeish I.A., Swisher E.M., Lin K., Scott C.L. (2017) Secondary somatic mutations restoring RAD51C and RAD51D associated with acquired resistance to the PARP inhibitor Rucaparib in high-grade ovarian carcinoma, Cancer Discovery, In press. https://www.ncbi.nlm.nih.gov/pubmed/28588062 |
3. |
Kong, M., Liu, L., Chen, X., Driscoll, K.I., Mao, P., Böhm, S., Kad, N.M., Watkins, S., Bernstein, K.A., Wyrick, J.J., Min, J.H., Van Houten, B. (2016) Single-molecule imaging reveals that Rad4 employs a dynamic DNA damage recognition process, Molecular Cell, 64(2): 376-387. https://www.ncbi.nlm.nih.gov/pubmed/27720644 |
4. |
Martino, J. and Bernstein, K.A. (2016) The Shu complex is a conserved regulator of homologous recombination, FEMS Yeast Research, 16(6): fow073. https://www.ncbi.nlm.nih.gov/pubmed/27589940 |
5. |
Godin, S.K., Zhang, Z., Herken, B.W., Westmoreland, J.W., Lee, A.G., Mihalevic, M.J., Yu, Z., Sobol, R.W., Resnick, M.A., Bernstein K.A. (2016) The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products, Nucleic Acids Research, 44(17): 8199-8215. http://www.ncbi.nlm.nih.gov/pubmed/27298254 |
6. |
Godin, S.K., Sullivan, M.R., Bernstein, K.A. (2016) Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication, Biochemistry and Cell Biology, 94: 1-12. http://www.ncbi.nlm.nih.gov/pubmed/27224545 |
7. |
McClendon, T.B.*, Sullivan, M.R.*, Bernstein, K.A.*, Yanowitz, J.L.* (2016) Promotion of homologous recombination by SWS-1 in complex with RAD-51 paralogs in Caenorhabditis elegans, Genetics, 203(1): 133-145. *Equal contribution http://www.ncbi.nlm.nih.gov/pubmed/26936927 *Featured as a Genetics Primer [Turcotte, C.A., Andrews, N.P., Sloat, S.A., Checchi, P.M. CRISPR Technology Reveals RAD(51)-ical Mechanisms of Repair in Roundworms: An Educational Primer for Use with “Promotion of Homologous Recombination by SWS-1- in Complex with RAD-51 Paralogs in Caenorhabditis elegans” (2016) Genetics 204: 883-891] |
8. |
Godin, S.K., Lee, A.G., Baird, J.M., Herken, B.W., Bernstein, K.A. (2016) Tryptophan biosynthesis is important for resistance to replicative stress in Saccharomyces cerevisiae, Yeast, 33(5): 183-189. http://www.ncbi.nlm.nih.gov/pubmed/26804060 |
9. |
Böhm, S., Szakal, B., Herken, B.W., Sullivan, M.R., Mihalevic, M.J., Kabbinavar, F.F., Branzei, D., Clark, N.L., Bernstein, K.A. (2016) The budding yeast ubiquitin protease Ubp7 is a novel component involved in S-phase progression, Journal of Biological Chemistry, 291(9): 4442. http://www.ncbi.nlm.nih.gov/pubmed/26740628 |
10. |
Gaines, W.*, Godin, S.K.*, Kabbinavar, F.F., VanDemark, A.P., Sung, P.*, Bernstein, K.A.* (2015) Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52, *Equal contribution, Nature Communications, 28(6): 7834. http://www.ncbi.nlm.nih.gov/pubmed/26215801 *Interviewed for Pittsburgh's National Public Radio Affiliate WESA *Featured on Futurity *Featured on GEN News Highlights |
11. |
Wei, L., Nakajima, S., Böhm, S. Bernstein, K.A., Shen, Z., Tsang, M., Levine, A.S., Lan, L. (2015) DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne Syndrome B-dependent homologous recombination, Proceedings of the National Academy of Sciences, 11(27): 3495-3504. http://www.ncbi.nlm.nih.gov/pubmed/26100862 |
12. |
Godin, S.K., Meslin, C., Kabbinavar F., Bratton-Palmer, D.S., Hornack, C., Mihalevic, M.J., Yoshida, K., Sullivan, M., Clark, N.L.*, Bernstein, K.A.* (2015) Evolutionary and functional analysis of the invariant SWIM domain in the conserved Shu2/SWS1 protein family from Saccharomyces cerevisiae to Homo sapiens, Genetics, 199(4): 1023-1033. *Joint corresponding http://www.ncbi.nlm.nih.gov/pubmed/25659377 *Issue Highlight *Featured as top news on SGD website http://www.yeastgenome.org/once-you-start-looking-shu2-homologs-are-everywhere |
13. |
Böhm, S., Mihalevic, M.J., Casal, M.A., and Bernstein, K.A. (2015) Disruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells, DNA Repair, 26: 1-14. http://www.ncbi.nlm.nih.gov/pubmed/25588990 |
14. |
Böhm, S. and Bernstein, K.A. (2014) The role of post-translational modifications in fine-tuning BLM helicase function during DNA repair, DNA Repair, 22: 123-132. http://www.ncbi.nlm.nih.gov/pubmed/25150915 |
15. |
Fu Q., Chow, J., Bernstein, K.A., Makharashvili, N., Arora, S., Lee, C.F., Person, M.D., Rothstein, R., Paull, T.T. (2014) Phosphorylation-regulated transitions in oligomeric state control the activity of the Sae2 DNA repair enzyme, Molecular and Cellular Biology, (34)5: 778-793. http://www.ncbi.nlm.nih.gov/pubmed/24344201 |
16. |
Bernstein, K.A., Mimitou, E.P., Mihalevic, M.J., Chen, H., Sunjaveric, I., Symington, L.S., Rothstein R. (2013) Resection activity of the Sgs1 helicase alters the affinity of DNA ends for homologous recombination proteins in Saccharomyces cerevisiae, Genetics, 195(4): 1241-1251. http://www.ncbi.nlm.nih.gov/pubmed/24097410 *Issue Highlight |
17. |
Bernstein, K.A., Juanchich, A., Sunjevaric, I., Rothstein, R. (2013) The Shu complex regulates Rad52 localization during rDNA repair, DNA Repair, 12(9): 786-790. http://www.ncbi.nlm.nih.gov/pubmed/23790361 |
18. |
Godin, S., Wier, A., Kabbinavar, F., Bratton-Palmer, D.S., Ghodke, H., Van Houten, B., VanDemark, A.P., and Bernstein, K.A. (2013) The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free recombination. Nucleic Acids Research, 41(8): 4525-4534. http://www.ncbi.nlm.nih.gov/pubmed/23460207 |
19. |
Karpenshif, Y. and Bernstein, K.A. (2012) From yeast to mammals: recent advances in genetic control of homologous recombination. DNA Repair, 11(10): 781-788. http://www.ncbi.nlm.nih.gov/pubmed/22889934 *One of five most downloaded DNA Repair articles in 2013 |
20. |
Robert, R., Vanoli, F., Chiolo, I., Shubassi, G., Bernstein, K.A., Rothstein, R., Botrugno, O.A., Parazzoli, D., Oldani, A., Miunuccci, S., Foiani, M. (2011) HDACs link the DNA damage response, processing of double-strand breaks and autophagy. Nature, 471(7336): 74-79. http://www.ncbi.nlm.nih.gov/pubmed/21368826 |
21. |
Bernstein, K.A., Reid, R.J., Sunjevaric, I., Burgess, R.C., Demuth, K., and Rothstein, R. (2011) The Shu complex, which contains Rad51 paralogues, promotes DNA repair through inhibition of the Srs2 anti-recombinase. Molecular Biology of the Cell, 22(9): 1599-1607. http://www.ncbi.nlm.nih.gov/pubmed/21372173 |
22. |
Bernstein, K.A., Gangloff, S., and Rothstein, R. (2010) The Role of the RecQ Helicases in DNA repair. Annual Review of Genetics, 44: 393-417. http://www.ncbi.nlm.nih.gov/pubmed/21047263 |
23. |
Bernstein, K.A. and Rothstein, R., (2009) At loose ends: Resecting a double strand break. Cell, 137(5): 807-810. http://www.ncbi.nlm.nih.gov/pubmed/19490890 |
24. |
Bernstein, K.A., Shor, E., Sunjevaric, I., Burgess, RC., Fumasoni, M., Foiani, M., Branzei, D., Rothstein R. (2009) The role of the Sgs1 helicase in DNA replication is separate from its role in recombinational repair. EMBO Journal. 28(7): 915-925. http://www.ncbi.nlm.nih.gov/pubmed/19214189 |
25. |
Bernstein, K.A., Bean J., Cross, F.R., and Baserga, S.J. (2007) Ribosome biogenesis directly promotes passage at Start through Whi5, the yeast homologue of Rb. Molecular Biology of the Cell. 18(3):953-964. http://www.ncbi.nlm.nih.gov/pubmed/17192414 |
26. |
Bernstein, K.A., Granneman, S., Lee, A.V., Manickam, S., and Baserga, S.J. (2005) A comprehensive mutational analysis of yeast DExD/H box RNA helicases involved in large ribosomal subunit biogenesis. Molecular and Cellular Biology. 26(4): 1195-1208. http://www.ncbi.nlm.nih.gov/pubmed/16449635 |
27. |
Granneman, S., Bernstein, K.A., Bleichart, F., and Baserga, S.J. (2005) A comprehensive mutational analysis of yeast DExD/H box RNA helicases involved in small ribosomal subunit biogenesis. Molecular and Cellular Biology. 26(4): 1183-1194. http://www.ncbi.nlm.nih.gov/pubmed/16449634 |
28. |
Bernstein, K.A., and Baserga, S.J. (2004). The SSU processome is required for cell cycle progression at G1. Molecular Biology of the Cell. 15(11): 5038-2046. http://www.ncbi.nlm.nih.gov/pubmed/15356263 |
29. |
Bernstein, K.A., Gallagher, J.E.G., Mitchell, B.M., Granneman, S., and Baserga, S.J. (2004). The SSU processome is a ribosome assembly intermediate. Eukaryotic Cell. 3(6): 1619-1626. http://www.ncbi.nlm.nih.gov/pubmed/15590835 |
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Former Name: Kara Porwancher |
30. |
Dragon, F., Gallagher, J.E., Compagnone-Post, P.A., Mitchell, B.M., Porwancher, K.A., Wehner, K.A., Wormsley, S., Settlage, R.E., Shabanowitz, J., Osheim, Y., Beyer, A.L., Hunt, D.F., and Baserga, S.J. (2002). A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis. Nature. 417: 967-970. http://www.ncbi.nlm.nih.gov/pubmed/12068309 *Recommended by Faculty of 1000 |
31. |
Alonso, M., Hamelin, R., Kim, M., Porwancher, K., Sung, T., Parhar, P., Miller, D.C., and Newcomb, E.W. (2001) Microsatellite instability occurs in distinct subtypes of pediatric but not adult central nervous system tumors. Cancer Research. 61: 2124-2128. http://www.ncbi.nlm.nih.gov/pubmed/11280776 |
